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Table 2 Most highly differentially expressed pathways comparing zero and eight hours post Salmonella infection in primary porcine neutrophils

From: Salmonella enterica serovar Typhimurium inhibits the innate immune response and promotes apoptosis in a ribosomal/TRP53-dependent manner in swine neutrophils

Pathway name Change direction Pathway genes count Pathway p-value
MicroRNA (miRNA) biogenesis Up 5 1.54E−04
Propanoate metabolism Up 6 4.63E−04
Pyruvate metabolism Up 7 6.62E−04
Double stranded RNA induced gene expression Up 4 0.001261
Huntington's disease Up 15 0.001402
Direct p53 effectors Up 12 0.001602
Nucleotide Excision Repair Up 8 0.001777
Pyruvate metabolism Up 6 0.002333
Regulatory RNA pathways Up 7 0.002367
mRNA Splicing Up 12 0.002379
mRNA Splicing—Major Pathway Up 12 0.002379
Purine catabolism Up 3 0.002959
Cleavage of Growing Transcript in the Termination Region Up 6 0.003025
RNA Polymerase II Transcription Termination Up 6 0.003025
Processing of Capped Intron-Containing PrE−mRNA Up 12 0.003051
Atm signaling pathway Up 4 0.003385
RNA Polymerase II Transcription Up 11 0.003468
HIV Infection Up 18 0.003569
Pyrimidine metabolism Up 9 0.004232
Inhibition of TSC complex formation by PKB Up 2 0.004779
Ribosome Down 12 3.01E−05
Cytokine-cytokine receptor interaction Down 14 9.58E−05
Interferon alpha/beta signaling Down 6 1.10E−04
Eukaryotic Translation Termination Down 9 3.07E−04
Peptide chain elongation Down 9 3.07E−04
Viral mRNA Translation Down 9 3.55E−04
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Down 9 4.67E−04
Eukaryotic Translation Elongation Down 9 4.67E−04
L13a-mediated translational silencing of Ceruloplasmin expression Down 10 5.85E−04
GTP hydrolysis and joining of the 60S ribosomal subunit Down 10 6.55E−04
Formation of a pool of free 40S subunits Down 9 9.93E−04
Cap-dependent Translation Initiation Down 10 0.001121
Eukaryotic Translation Initiation Down 10 0.001121
Class A/1 (Rhodopsin-like receptors) Down 16 0.00113
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Down 9 0.001556
Nonsense-Mediated Decay (NMD) Down 9 0.001556
Acyl chain remodelling of PI Down 2 0.001704
Acyl chain remodelling of PS Down 2 0.001704
Binding and entry of HIV virion Down 2 0.001704
SRP-dependent cotranslational protein targeting to membrane Down 9 0.002351
Influenza Viral RNA Transcription and Replication Down 9 0.002855
Signaling by GPCR Down 24 0.004493
Influenza Life Cycle Down 9 0.004493
Influenza Infection Down 9 0.004895
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha Down 2 0.004973